Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014167 | 0.83 | POLB (0.61) | MAPTLMNASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL23014364 | 0.82 | DRD2 (0.66) | DRD4POLB | |
| SCHEMBL23014160 | 0.81 | CHRM3 (0.61) | LMNASMN1; SMN2L3MBTL1MAPK1TSHR | |
| SCHEMBL23014343 | 0.79 | ALDH1A1 (0.60) | MAPTSMN1; SMN2MAPK1HPGDHTT | |
| SCHEMBL23014286 | 0.79 | HTR1A (0.55) | TSHRHTTDRD4HSD17B10KMT2A | |
| SCHEMBL23014309 | 0.78 | CACNA1G (0.52) | SMN1; SMN2L3MBTL1MAPK1TSHRHPGD | |
| SCHEMBL23014151 | 0.77 | ALDH1A1 (0.56) | MAPTLMNASMN1; SMN2MAPK1TSHR | |
| SCHEMBL27040179 | 0.77 | HTR7 (0.62) | MAPTLMNASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL23014291 | 0.77 | KDM4E (0.52) | MAPTLMNASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL29733707 | 0.77 | KDM4E (0.52) | MAPTLMNASMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019495-A1 | NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND | Cellgentek Co., Ltd (KR) | 2022-06-29 | — | — | EP | disclosed |