Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 4/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167444 | 0.86 | CSF1R (0.46) | METCSF1RTYRO3LDHALDHB | |
| SCHEMBL21167604 | 0.84 | CSF1R (0.62) | METCSF1RLDHALDHB | |
| SCHEMBL21167754 | 0.84 | MET (0.60) | METCSF1RTYRO3ATRPIK3CD | |
| SCHEMBL21167393 | 0.83 | MET (0.44) | METCSF1RTYRO3PIK3CDPIK3CB | |
| SCHEMBL21167601 | 0.78 | CSF1R (0.40) | METCSF1RPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24590986 | 0.78 | MET (0.59) | METCSF1RTYRO3PIK3CDPIK3CB | |
| SCHEMBL21167443 | 0.76 | MET (0.42) | METCSF1RPDE10A | |
| SCHEMBL24591017 | 0.74 | MET (0.43) | METCSF1RPDE10A | |
| SCHEMBL22475943 | 0.74 | MET (0.59) | METCSF1RTYRO3PIM1PIM3 | |
| SCHEMBL12689739 | 0.74 | MET (0.73) | METPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795573-B1 | CERTAIN TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LTD (CN) | 2022-07-06 | — | — | EP | disclosed |