SCHEMBL245954

SCHEMBL245954

CC1=C(N2CCCCC2)C(=O)c2ccccc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 7/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
MAPT P10636 8/20 0.59
ALDH1A1 P00352 6/20 0.59
SMN1; SMN2 Q16637 5/20 0.59
HTT P42858 4/20 0.59
LMNA P02545 3/20 0.59
POLB P06746 2/20 0.59
MITF O75030 1/20 0.59
KLF5 Q13887 1/20 0.59
NPSR1 Q6W5P4 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
NSD2 O96028 4/20 0.53
TDP2 O95551 3/20 0.53
HKDC1 Q2TB90 1/20 0.53
MAPK1 P28482 3/20 0.52
PTBP1 P26599 1/20 0.52
PKM P14618 3/20 0.51
L3MBTL1 Q9Y468 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1242685 0.92 MAPT (0.67) APAF1NPC1RAB9AMAPTALDH1A1
Hydrochloric Acid SCHEMBL4204889 0.91 APAF1 (0.56) APAF1NPC1RAB9AMAPTALDH1A1
Hydrochloric Acid SCHEMBL4204888 0.91 APAF1 (0.60) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL17249924 0.84 TDP2 (0.71) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL10556309 0.82 HTR7 (0.50) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL10446114 0.80 NSD2 (0.71) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL10560224 0.78 TDP2 (0.48) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL8568869 0.78 NSD2 (0.73) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL14567092 0.78 ALDH1A1 (0.51) APAF1NPC1RAB9AMAPTALDH1A1
SCHEMBL10446742 0.77 APAF1 (0.39) APAF1NPC1RAB9AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-9271669-B2 Method for integrated sample acquisition and analyte measurement device ABBOTT DIABETES CARE INC. (US) 2016-03-01 US disclosed
US-9234863-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-01-12 US disclosed
US-20030199744-A1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. (US) 2003-10-23 US disclosed
US-6618934-B1 Method of manufacturing small volume in vitro analyte sensor THERASENSE, INC. 2003-09-16 US disclosed
US-6592745-B1 Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care THERASENSE, INC. 2003-07-15 US disclosed
US-6591125-B1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. 2003-07-08 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
CN-1322254-A Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator THERASENSE INC (US) 2001-11-14 CN disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
EP-1119637-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR Therasense, Inc. (US) 2001-08-01 EP disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed