Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL7588983 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL537674 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL5242240 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL6572404 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1070309 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1947696 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1948761 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1949022 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL2754253 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL9288979 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107236017-A | Gypsogenin derivative | 山东省医学科学院药物研究所 | 2017-10-10 | — | — | CN | disclosed |
| EP-2374802-A1 | KYNURENINE PRODUCTION INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA KIRIN CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-1498421-B1 | GAMMA-SECRETASE INHIBITORS | MORI HIROSHI (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7585938-B2 | Gamma-secretase inhibitors | MORI HIROSHI | 2009-09-08 | — | — | US | disclosed |
| CN-1319987-C | Gamma-secretase inhibitors | HIROSHI MORI (JP) | 2007-06-06 | — | — | CN | disclosed |
| US-20060205666-A1 | Gamma-secretase inhibitors | MORI HIROSHI | 2006-09-14 | — | — | US | disclosed |
| CN-1656115-A | Gamma-secretase inhibitors | HIROSHI MORI (JP) | 2005-08-17 | — | — | CN | disclosed |
| EP-1498421-A1 | GAMMA-SECRETASE INHIBITORS | Mori, Hiroshi (JP) | 2005-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205666-A1 | Gamma-secretase inhibitors | BACE1, BACE2, PSENEN | ALDH1A1 4529/4885TDP1 1214/4885TRPA1 4376/4885 |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYNU, KMO, IDO1 | ALDH1A1 1689/4885TDP1 2717/4885TRPA1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.