Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL7588983 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL5242240 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL6572404 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1070309 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1947696 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1948761 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL2459693 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL1949022 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL2754253 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 | |
| Chloroform SCHEMBL9288979 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150367-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2024-05-09 | — | — | US | disclosed |
| US-20230023377-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | JAPAN TOBACCO INC. (JP) | 2023-01-26 | — | — | US | disclosed |
| EP-3858349-A1 | NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME | Japan Tobacco Inc. (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-10270101-B2 | Electrode active material for power storage device, and power storage device | PANASONIC CORPORATION (JP) | 2019-04-23 | — | — | US | disclosed |
| EP-3181570-A1 | NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME | Japan Tobacco Inc. (JP) | 2017-06-21 | — | — | EP | disclosed |
| EP-2460806-B1 | NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME | JAPAN TOBACCO INC (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20150295244-A1 | ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, AND POWER STORAGE DEVICE | PANASONIC CORPORATION (JP) | 2015-10-15 | — | — | US | disclosed |
| US-9108957-B2 | 3-[1,4]oxazepane-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140187534-A1 | NITROGEN-CONTAINING SPIROCYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | JAPAN TOBACCO INC. (JP) | 2014-07-03 | — | — | US | disclosed |
| US-8609647-B2 | Nitrogen-containing spirocyclic compounds and pharmaceutical uses thereof | JAPAN TOBACCO INC. (JP) | 2013-12-17 | — | — | US | disclosed |
| US-6239168-B1 | ANTITUMOR AGENTS, IMMUNOSUPPRESSANTS; TYROSINE KINASE INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| CN-1211244-A | Radicicol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1999-03-17 | — | — | CN | disclosed |
| EP-0889042-A1 | RADICICOL DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5696001-A | DETECTION OF HYDROLASES | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5648229-A | DETECTION OF HYDROLYTIC ENZYMES | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| US-5606035-A | ANTIOXIDANT FOR FOOD | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5585247-A | FLUORESCENT DYES FOR ENZYME IMMUNOASSAY | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| EP-0490765-A2 | 1-Arylsulfonyl-2-pyrrolidone-derivatives, process for their preparation, new in termediates, use for medicaments and drugs containing them | ROUSSEL-UCLAF (FR) | 1992-06-17 | — | — | EP | disclosed |
| US-5077200-A | Detection of hydrolyzing enzymes | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| US-4845030-A | DETECTION OF HYDROGEN PEROXIDE OR PERROXIDASE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230023377-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | REN, PKD1, NPR1 | ALDH1A1 985/4885TDP1 4699/4885TRPA1 267/4885 |
| US-10270101-B2 | Electrode active material for power storage device, and power storage device | HCN2, POLQ, KCNN2 | ALDH1A1 2120/4885TDP1 441/4885TRPA1 344/4885 |
| US-20140187534-A1 | NITROGEN-CONTAINING SPIROCYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | REN, PKD1, NR3C2 | ALDH1A1 651/4885TDP1 4762/4885TRPA1 226/4885 |
| US-20240150367-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USE THEREOF | REN, PKD1, NPR1 | ALDH1A1 936/4885TDP1 4671/4885TRPA1 256/4885 |
| US-20150295244-A1 | ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, AND POWER STORAGE DEVICE | NDUFV2, NDUFA2, SSBP1 | ALDH1A1 716/4885TDP1 2638/4885TRPA1 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.