SCHEMBL2459985

SCHEMBL2459985

O=C(O)CCOP(=O)(OCCC(=O)O)OCCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
LMNA P02545 7/20 0.42
EGLN1 Q9GZT9 2/20 0.42
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42
CYP3A4 P08684 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.38
TSHR P16473 5/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
FFAR3 O14843 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
FOLH1 Q04609 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL502062 0.97 ALDH1A1 (0.42) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL10009881 0.85 ALDH1A1 (0.45) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL2710223 0.81 LPAR3 (0.43) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL9054631 0.80 ALDH1A1 (0.61) ALDH1A1LMNACYP3A4SLC22A6TSHR
SCHEMBL27692979 0.79 ALDH1A1 (0.43) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL1877200 0.79 ALDH1A1 (0.43) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL27566719 0.79 LPAR3 (0.41) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
Hydrochloric Acid SCHEMBL22189200 0.79 LPAR3 (0.41) ALDH1A1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL5472579 0.79 TSHR (0.55) ALDH1A1TSHRHDAC3HDAC1HDAC2
SCHEMBL8028544 0.77 ALDH1A1 (0.46) ALDH1A1LMNAEGLN1ALKBH5SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496222-A Selenium-containing melanin and preparation method and application thereof 北京师范大学 2024-08-16 CN claimed
CN-116064959-A Colorimetric sensor and kit based on CRISPR-Cas12a and application of colorimetric sensor and kit in detection of viral nucleic acid 山东师范大学 2023-05-05 CN claimed
CN-115286958-B Biomass-based antifouling material and application thereof 陕西师范大学 2023-04-07 CN claimed
CN-115286958-A Biomass-based antifouling material and application thereof 陕西师范大学 2022-11-04 CN claimed
CN-112876862-B Nano ferroferric oxide/bovine serum albumin composite material, preparation method and application 西安理工大学 2022-05-17 CN claimed
CN-113897414-A Trace nucleic acid library construction method 湖南大地同年生物科技有限公司 2022-01-07 CN claimed
CN-112876862-A Nano ferroferric oxide/bovine serum albumin composite material, preparation method and application 西安理工大学 2021-06-01 CN claimed
CN-112264272-A Multifunctional natural super-hydrophobic material and application thereof 陕西师范大学 2021-01-26 CN claimed
CN-107573530-B Preparation method of lysozyme composite food packaging film 西安理工大学 2020-08-18 CN claimed
CN-111135345-A Dental implant material and preparation method thereof 吴俊江 2020-05-12 CN claimed
WO-2026097979-A1 FLAME-RETARDANT MATERIAL, AND PREPARATION METHOD THEREFOR AND PRODUCT THEREOF 江苏博云塑业股份有限公司 2026-05-15 WO disclosed
US-12583920-B2 Compositions and methods for treatment and prevention of Alzheimer's disease UNIVERSITY OF MARYLAND, BALTIMORE (US) 2026-03-24 US disclosed
US-20260015332-A1 SYNTHESIS METHOD AND APPLICATION OF BENZOTHIASELENAZOLE-1-OXIDE COMPOUND AND DERIVATIVE THEREOF GUANGZHOU MEDICAL UNIVERSITY (CN) 2026-01-15 US disclosed
CN-120081920-A Disulfide bond-containing polypeptide and preparation method and application thereof 中国科学院上海药物研究所 2025-06-03 CN disclosed
CN-120078709-A Multifunctional nano hydrogel and preparation method and application thereof 上海交通大学医学院附属第九人民医院 2025-06-03 CN disclosed
US-20080207541-A1 Contacting a eukaryotic cell with a mixed backbone oligonucleotide with a first region that forms a substrate for cleavage by an RNase and a second region which does not, and a transition moiety which modulates the transmission of the conformation of said second region into the first region IONIS PHARMACEUTICALS, INC. 2008-08-28 US disclosed
US-20080118916-A1 SEQUENTIAL ANALYSIS OF BIOLOGICAL SAMPLES GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
EP-1730309-A2 COMPOSITIONS AND METHODS FOR OPTIMIZING CLEAVAGE OF RNA BY RNASE H Isis Pharmaceuticals, Inc. (US) 2006-12-13 EP disclosed
WO-2005089268-A2 COMPOSITIONS AND METHODS FOR OPTIMIZING CLEAVAGE OF RNA BY RNASE H ISIS PHARMACEUTICALS, INC. (US) 2005-09-29 WO disclosed
US-6657196-B2 Method and apparatus for environmental monitoring ADVANTEST CORP. (JP) 2003-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207541-A1 Contacting a eukaryotic cell with a mixed backbone oligonucleotide with a first region that forms a substrate for cleavage by an RNase and a second region which does not, and a transition moiety which modulates the transmission of the conformation of said second region into the first region RNASEH1, NSUN3, RNASEL ALDH1A1 3259/4885LMNA 453/4885EGLN1 1093/4885
US-12583920-B2 Compositions and methods for treatment and prevention of Alzheimer's disease APP, MAPT, LRP6 ALDH1A1 3125/4885LMNA 1753/4885EGLN1 4724/4885
US-20260015332-A1 SYNTHESIS METHOD AND APPLICATION OF BENZOTHIASELENAZOLE-1-OXIDE COMPOUND AND DERIVATIVE THEREOF SARS1, EGFR, ERBB2 ALDH1A1 2251/4885LMNA 4526/4885EGLN1 4017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.