Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459985 | 0.97 | ALDH1A1 (0.43) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL10009881 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| Hydrochloric Acid SCHEMBL22189200 | 0.82 | LPAR3 (0.41) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL2710223 | 0.79 | LPAR3 (0.43) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL9054631 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNACYP3A4SLC22A6TSHR | |
| Hydrochloric Acid SCHEMBL26114432 | 0.78 | ALDH1A1 (0.35) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL27566719 | 0.77 | LPAR3 (0.41) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL27692979 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL1877200 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL5472579 | 0.77 | TSHR (0.55) | ALDH1A1TSHRHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823707-A | Hot-melt injectable adhesive, and preparation method and application thereof | 四川大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119488100-A | Preparation method and application of dual-response controlled-release pesticide | 塔里木大学 | 2025-02-21 | — | — | CN | claimed |
| CN-119060634-A | Protein adhesion super-slip coating and application thereof | 陕西师范大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118995763-A | Method for synthesizing ergothioneine by biological enzyme method | 深圳中科欣扬生物科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118490850-A | Photoacoustic contrast agent based on reversible photoswitch fusion protein, and preparation method and application thereof | 深圳大学 | 2024-08-16 | — | — | CN | claimed |
| CN-117753446-A | Noble metal coated silver-based core-shell structure nano material, preparation method and application thereof | 南京邮电大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117705998-A | Novel EDURISP proteomics sample pretreatment method | 天津市眼科医院 | 2024-03-15 | — | — | CN | claimed |
| CN-117551817-A | Target gene, primer probe combination, kit and application for detecting influenza A virus | 天津欧德莱生物医药科技有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117339022-A | Silk fibroin-based hydrogel double-layer composite membrane and preparation method thereof | 浙江省人民医院 | 2024-01-05 | — | — | CN | claimed |
| CN-117304917-A | Magnetic fluorescent functional microsphere and preparation method and application thereof | 上海祎飞生物科技有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117164681-A | Dengue polypeptide vaccine based on spherical nucleic acid vector and preparation method and application thereof | 中国人民解放军陆军军医大学 | 2023-12-05 | — | — | CN | claimed |
| CN-116982654-A | Protein-based edible fruit preservative solution | 陕西师范大学 | 2023-11-03 | — | — | CN | claimed |
| CN-122060354-A | Protein in-situ self-assembly-based anti-fouling coating for internal seawater system, and preparation method and application thereof | 华南理工大学 | 2026-05-19 | — | — | CN | disclosed |
| EP-4720339-A1 | METHODS FOR DOUBLE-STRANDED SEQUENCING BY SYNTHESIS | Illumina, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12559795-B2 | Compositions, methods, kits, cartridges, and systems for sequencing reagents | ILLUMINA, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250382609-A1 | METHODS AND COMPOSITIONS USING ONE-SIDED TRANSPOSITION | ILLUMINA, INC. (US) | 2025-12-18 | — | — | US | disclosed |
| WO-2007091077-A1 | METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE | SOLEXA LIMITED (GB) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007010252-A1 | METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE | SOLEXA LIMITED (GB) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007010254-A1 | METHODS OF NUCLEIC ACID AMPLIFICATION AND SEQUENCING | SOLEXA LIMITED (GB) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006064199-A1 | IMPROVED METHOD OF NUCLEOTIDE DETECTION | SOLEXA LIMITED (GB) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559795-B2 | Compositions, methods, kits, cartridges, and systems for sequencing reagents | RNGTT, PHAX, RNMT | HDAC3 2985/4885HDAC1 3596/4885HDAC2 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.