Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427195 | 0.89 | MAPT (0.48) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29427192 | 0.88 | MAPT (0.51) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24601168 | 0.84 | MAOB (0.63) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2239741 | 0.79 | ATP6V1B1 (0.51) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL2239744 | 0.79 | ATP6V1B1 (0.51) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL24601450 | 0.79 | MMP13 (0.72) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL951357 | 0.78 | ALDH1A1 (0.59) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL951355 | 0.78 | ALDH1A1 (0.59) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL24601171 | 0.76 | CYP2A6 (0.44) | MAOBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL19592652 | 0.76 | VCP (0.47) | MAOBMAOANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | HNRNPF, RBM3, RBM15 | MAOB 3990/4885MAOA 4560/4885NPC1 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.