SCHEMBL24601672

SCHEMBL24601672

CC(C)(C)c1ccc(-c2ccc3c(c2)c2c4c5ccc(-c6ccc(C(C)(C)C)cc6)cc5n5c6ccc(-c7ccc(C(C)(C)C)cc7)cc6c(c6c7ccc(-c8ccc(C(C)(C)C)cc8)cc7n3c26)c45)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.36
SERPINE1 P05121 4/20 0.34
HTR1D P28221 1/20 0.32
OPRD1 P41143 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
ICMT O60725 3/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTGES O14684 1/20 0.31
GSK3B P49841 1/20 0.31
SRC P12931 2/20 0.31
PRKACA P17612 2/20 0.31
PRKACG P22612 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601484 0.94 KIF11 (0.40) KIF11SERPINE1HTR1DCA12CA9
SCHEMBL24601344 0.90 ALDH1A1 (0.37) KIF11SERPINE1KDM4EALDH1A1HSD17B2
SCHEMBL24601540 0.90 ALDH1A1 (0.37) KIF11SERPINE1KDM4EALDH1A1HSD17B2
SCHEMBL24601457 0.90 TSPO (0.38) KIF11SERPINE1KDM4EALDH1A1HSD17B2
SCHEMBL24601542 0.90 TSPO (0.38) KIF11SERPINE1KDM4EALDH1A1HSD17B2
SCHEMBL24601483 0.90 RXRB (0.36) SERPINE1ICMT
SCHEMBL24601441 0.87 HTR1D (0.35) SERPINE1HTR1DICMT
SCHEMBL24601401 0.87 SERPINE1 (0.37) KIF11SERPINE1ALDH1A1HSD17B2
SCHEMBL24601425 0.85 RXRA (0.35) KIF11SERPINE1HTR1DALDH1A1HSD17B2
SCHEMBL24601485 0.83 RXRB (0.40) KIF11ICMTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 KIF11 3347/4885SERPINE1 4819/4885HTR1D 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.