SCHEMBL24602248

SCHEMBL24602248

c1ccc(-c2ccc(-c3nc(-c4cc5ccccc5c5ccccc45)nc(-c4cccc5oc6c(-c7ccc(-c8ccccc8)cc7)cccc6c45)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.40
▸ MAPT P10636 6/20 0.37
▸ ALDH1A1 P00352 6/20 0.36
▸ KDM4E B2RXH2 5/20 0.36
▸ TSHR P16473 4/20 0.36
▸ HPGD P15428 3/20 0.36
▸ MAPK1 P28482 3/20 0.36
▸ HSD17B10 Q99714 3/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ TP53 P04637 1/20 0.36
▸ NFKB1 P19838 1/20 0.36
▸ NFKB2 Q00653 1/20 0.36
▸ RELA Q04206 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ GPR84 Q9NQS5 1/20 0.36
▸ CASP1 P29466 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23820930 1.00 ALOX5 (0.40) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24602133 1.00 ALOX5 (0.40) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24602120 0.98 ALOX5 (0.38) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24602004 0.98 ALOX5 (0.38) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL23821358 0.98 ALOX5 (0.39) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24602253 0.97 ALDH1A1 (0.40) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24886617 0.96 ALOX5 (0.40) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24601986 0.95 ALOX5 (0.41) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL24601921 0.95 ALDH1A1 (0.38) ALOX5MAPTALDH1A1KDM4ETSHR
SCHEMBL23819515 0.95 ALDH1A1 (0.40) ALOX5MAPTALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 — — US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 — — US disclosed
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 — — US disclosed
US-20220213116-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213116-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF PIEZO1, LEF1, TMEM109 ALOX5 693/4885MAPT 1596/4885ALDH1A1 129/4885
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 ALOX5 1042/4885MAPT 2059/4885ALDH1A1 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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