Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434191 | 0.75 | TRPA1 (0.39) | TRPA1ALDH1A1 | |
| SCHEMBL8048267 | 0.70 | — | — | |
| SCHEMBL4438144 | 0.66 | TRPA1 (0.46) | TRPA1ALDH1A1 | |
| SCHEMBL140868 | 0.66 | — | — | |
| SCHEMBL2460300 | 0.66 | CYP2C19 (0.43) | TRPA1ALDH1A1 | |
| SCHEMBL2464546 | 0.64 | — | — | |
| SCHEMBL17768384 | 0.64 | — | — | |
| SCHEMBL6063687 | 0.63 | — | — | |
| SCHEMBL16904007 | 0.62 | — | — | |
| SCHEMBL5987028 | 0.62 | TRPA1 (0.42) | TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697447-B2 | Cleavable surfactants and methods of use thereof | VANDERBILT UNIVERSITY (US) | 2014-04-15 | — | — | US | disclosed |
| US-20110217783-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY | 2011-09-08 | — | — | US | disclosed |
| EP-1404643-A4 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | UNIV VANDERBILT (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20060240562-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | CAPRIOLI RICHARD M | 2006-10-26 | — | — | US | disclosed |
| US-7074936-B2 | Cleavable surfactants and methods of use thereof | VANDERBILT UNIVERSITY (US) | 2006-07-11 | — | — | US | disclosed |
| US-20040152913-A1 | Cleavable surfactants and methods of use thereof | VANDERBILT UNIVERSITY | 2004-08-05 | — | — | US | disclosed |
| EP-1404643-A2 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002097393-A2 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110217783-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | PHOSPHO1, SGMS1, SGMS2 | TRPA1 3212/4885ALDH1A1 4849/4885 |
| US-20060240562-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | ADAM33, ADAM17, TMPRSS15 | TRPA1 4180/4885ALDH1A1 4845/4885 |
| US-20040152913-A1 | Cleavable surfactants and methods of use thereof | ADAM33, ADAM17, TMPRSS15 | TRPA1 4180/4885ALDH1A1 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.