Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22222937 | 0.88 | CA2 (0.44) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| SCHEMBL12094201 | 0.85 | PTGS2 (0.54) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| SCHEMBL20369612 | 0.84 | CA2 (0.55) | HTR2AHTR2CKCNH2CA2SMN1; SMN2 | |
| SCHEMBL28039981 | 0.84 | KDM4E (0.50) | HTR2AHTR2CKCNH2CA2MAPT | |
| SCHEMBL568140 | 0.79 | LOXL2 (0.47) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| SCHEMBL23530021 | 0.79 | PTGS2 (0.43) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| SCHEMBL14760478 | 0.79 | PTGS2 (0.43) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| SCHEMBL1853274 | 0.78 | LMNA (0.42) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| Hydrochloric Acid SCHEMBL560818 | 0.78 | LOXL2 (0.49) | MBOAT4HTR2AHTR2CKCNH2PTGS2 | |
| SCHEMBL28366503 | 0.77 | HTR2A (0.38) | MBOAT4HTR2AHTR2CKCNH2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |