Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614732 | 0.90 | ALDH1A1 (0.41) | TTRMAOAALDH1A1KDM4EMEN1 | |
| SCHEMBL16283913 | 0.87 | TDP1 (0.45) | TTRMAOAALDH1A1KDM4EMEN1 | |
| SCHEMBL24614975 | 0.84 | TTR (0.38) | TTRMAOAALDH1A1KDM4EMEN1 | |
| SCHEMBL24614840 | 0.82 | MAOA (0.39) | TTRMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL12811238 | 0.81 | AHR (0.47) | TTRMAOAALDH1A1KDM4EMEN1 | |
| SCHEMBL24614813 | 0.81 | TTR (0.36) | TTRMAOAALDH1A1KDM4EMEN1 | |
| SCHEMBL26380598 | 0.80 | KMT2A (0.42) | TTRMAOAALDH1A1KDM4EMEN1 | |
| SCHEMBL10109864 | 0.79 | HNF4A (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL24614772 | 0.79 | ALDH1A1 (0.41) | MAOAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL26634699 | 0.79 | CYP1A2 (0.47) | MAOAALDH1A1KDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | TTR 1412/4885MAOA 418/4885ALDH1A1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.