SCHEMBL2461485

SCHEMBL2461485

Cc1nc(N)c2ncn([C@@H]3O[C@H](CS)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.63
DNMT3B Q9UBC3 1/20 0.63
LMNA P02545 1/20 0.61
NT5E P21589 1/20 0.61
HIF1A Q16665 1/20 0.61
ADORA2A P29274 5/20 0.61
ADORA2B P29275 3/20 0.61
RNASEL Q05823 1/20 0.60
ADORA3 P0DMS8 4/20 0.60
ADORA1 P30542 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Methyladenosine SCHEMBL6934268 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
SCHEMBL8331180 0.91 DNMT1 (0.63) DNMT1DNMT3BLMNANT5EHIF1A
2-Methyladenosine SCHEMBL17124834 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
SCHEMBL19843956 0.91 DNMT1 (0.63) DNMT1DNMT3BLMNANT5EHIF1A
2-Methyladenosine SCHEMBL18159462 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL14075776 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512845 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512844 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL278664 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL13403859 0.91 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 EP claimed
EP-4306643-A2 PLASMID CONTAINING A SEQUENCE ENCODING AN MRNA WITH A SEGMENTED POLY(A) TAIL ethris GmbH (DE) 2024-01-17 EP claimed
US-20230165887-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2023-06-01 US claimed
CN-115418686-B Through hole high-depth copper electroplating solution for glass substrate and copper electroplating process thereof 深圳创智芯联科技股份有限公司 2023-01-10 CN claimed
CN-115418686-A Through hole high-depth copper electroplating solution for glass substrate and copper electroplating process thereof 深圳创智芯联科技股份有限公司 2022-12-02 CN claimed
US-10953031-B2 Compounds and methods for treating neurological and cardiovascular conditions ASTROCYTE PHARMACEUTICALS, INC. (US) 2021-03-23 US claimed
US-20200046751-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS, INC. 2020-02-13 US claimed
CN-103384496-A Blood collection devices containing blood stabilization agent BECTON DICKINSON CO 2013-11-06 CN claimed
EP-2645932-A2 BLOOD COLLECTION DEVICES CONTAINING BLOOD STABILIZATION AGENT Becton, Dickinson and Company (US) 2013-10-09 EP claimed
EP-1850134-B1 Method and Apparatus for the determination of the Thromboyte function and flow conditions SIEMENS HEALTHCARE DIAGNOSTICS (DE) 2013-01-30 EP claimed
WO-2012075407-A2 BLOOD COLLECTION DEVICES CONTAINING BLOOD STABILIZATION AGENT BECTON, DICKINSON AND COMPANY (US) 2012-06-07 WO claimed
EP-1850135-B1 Method for determining the thrombocyte function and flow conditions SIEMENS HEALTHCARE DIAGNOSTICS (DE) 2010-11-03 EP claimed
WO-2008113072-A2 GPCR ENHANCED NEUROPROTECTION TO TREAT BRAIN INJURY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-09-18 WO claimed
WO-2026110843-A1 METHOD FOR EVALUATING OXIDATION STRESS LEVEL 国立大学法人東北大学 (JP) 2026-05-28 WO disclosed
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 EP disclosed
WO-2026104647-A1 VACCINE ASTRAZENECA AB (SE) 2026-05-21 WO disclosed
EP-0364559-A4 SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS 1991-01-09 EP disclosed
EP-0364559-A1 SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS. SCRIPPS CLINIC RES (US) 1990-04-25 EP disclosed
WO-1989008658-A1 SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1989-09-21 WO disclosed
US-4687733-A Early cancer detection method OHIO STATE UNIVERSITY (US) 1987-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10953031-B2 Compounds and methods for treating neurological and cardiovascular conditions TNNI3, CPT1B, TNNT2 DNMT1 2348/4885DNMT3B 2551/4885LMNA 573/4885
US-20200046751-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 DNMT1 2348/4885DNMT3B 2551/4885LMNA 573/4885
US-20230165887-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 DNMT1 2348/4885DNMT3B 2551/4885LMNA 573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.