SCHEMBL24614934

SCHEMBL24614934

c1ccc(-c2c3ccccc3c(-c3cc4cc(-c5c6ccccc6c(-c6ccc7ccc8ccccc8c7c6)c6ccccc56)c5sc6ccccc6c5c4c4c3sc3ccccc34)c3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.35
CYP1B1 Q16678 2/20 0.33
NQO1 P15559 1/20 0.33
NQO2 P16083 1/20 0.33
CYP1A1 P04798 1/20 0.33
ALOX5 P09917 2/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SOS1 Q07889 1/20 0.32
PTPRC P08575 1/20 0.32
PTPRF P10586 1/20 0.32
PTPRA P18433 1/20 0.32
PTPRB P23467 1/20 0.32
PTPN6 P29350 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24614686 0.91 GPR84 (0.36) PTPN1CYP1B1NQO1NQO2CYP1A1
SCHEMBL24614750 0.90 PTPN1 (0.39) PTPN1ALOX5TNKSTNKS2PTPRC
SCHEMBL24614685 0.90 PTPN1 (0.41) PTPN1ALOX5TNKSTNKS2MEN1
SCHEMBL24614763 0.89 NQO2 (0.35) PTPN1CYP1B1NQO1NQO2ALOX5
SCHEMBL24614924 0.89 CYP1A1 (0.38) PTPN1CYP1B1NQO1NQO2CYP1A1
SCHEMBL24614682 0.88 S1PR5 (0.36) PTPN1CYP1B1CYP1A1ALOX5TNKS
SCHEMBL24614694 0.88 F9 (0.40) PTPN1CYP1B1CYP1A1ALOX5LIMK1
SCHEMBL24614680 0.88 ALOX5 (0.36) PTPN1CYP1B1NQO1NQO2CYP1A1
SCHEMBL24614753 0.86 PTPN1 (0.37) PTPN1ALOX5TNKSTNKS2PTPRC
SCHEMBL24614768 0.86 PTPN1 (0.40) PTPN1ALOX5TNKSTNKS2PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220223801-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220223801-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES TMEM109, PIEZO1, L1CAM PTPN1 4341/4885CYP1B1 10/4885NQO1 497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.