Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614686 | 0.96 | GPR84 (0.36) | S1PR5S1PR4GPR84PTPN1ALOX5 | |
| SCHEMBL24614753 | 0.92 | PTPN1 (0.37) | HSD17B1HSD17B2PTPN1ALOX5ESR1 | |
| SCHEMBL24614940 | 0.91 | HSD17B1 (0.33) | S1PR5S1PR4HSD17B1HSD17B2GPR84 | |
| SCHEMBL24614934 | 0.88 | PTPN1 (0.35) | PTPN1ALOX5ESR1ESR2CYP1A1 | |
| SCHEMBL24614750 | 0.88 | PTPN1 (0.39) | GPR84PTPN1ALOX5ESR1ESR2 | |
| SCHEMBL24614685 | 0.88 | PTPN1 (0.41) | PTPN1ALOX5ESR1ESR2TNKS | |
| SCHEMBL24614677 | 0.87 | F9 (0.37) | S1PR5S1PR4GPR84PTPN1ALOX5 | |
| SCHEMBL17944615 | 0.87 | ALOX5 (0.37) | S1PR5S1PR4HSD17B1HSD17B2GPR84 | |
| SCHEMBL24614768 | 0.87 | PTPN1 (0.40) | GPR84PTPN1ALOX5TNKSTNKS2 | |
| SCHEMBL24614804 | 0.86 | MAPT (0.34) | S1PR5S1PR4GPR84PTPN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | S1PR5 4028/4885S1PR4 3875/4885HSD17B1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.