SCHEMBL24614980

SCHEMBL24614980

CN(CCO[Si](C)(C)C(C)(C)C)CCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LTA4H P09960 10/20 0.38
KDM4C Q9H3R0 8/20 0.34
KDM5A P29375 7/20 0.34
KDM5C P41229 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
PHF8 Q9UPP1 2/20 0.33
KDM4A O75164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30420680 0.90 KDM4C (0.39) LTA4HKDM4CKDM5AKDM5CKDM5B
SCHEMBL24614982 0.87 MEN1 (0.58) MEN1KMT2ALTA4HKDM5A
SCHEMBL24614981 0.85 BLM (0.32) KDM4CKDM5APHF8
SCHEMBL26650890 0.84 LTA4H (0.40) LTA4HKDM4CKDM5AKDM5CKDM5B
SCHEMBL20660409 0.82 DRD2 (0.32)
SCHEMBL31399552 0.81 MEN1 (0.46) MEN1KMT2ALTA4HKDM4CKDM5A
SCHEMBL26962148 0.80
SCHEMBL6534167 0.80 ALDH1A1 (0.34) KDM5CPHF8
SCHEMBL20660298 0.80 CHRNB2 (0.41)
SCHEMBL5320462 0.79 LMNA (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4256067-A2 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF Tidal Therapeutics, Inc. (US) 2023-10-11 EP disclosed
US-20220218614-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2022-07-14 US disclosed
US-20220218614-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2022-07-14 US disclosed
WO-2022120388-A2 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2022-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220218614-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF LIPA, PHOSPHO1, SGMS1 MEN1 2364/4885KMT2A 2113/4885LTA4H 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.