Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24623222 | 0.90 | HPGD (0.65) | POLBCA12CA1CA9ALDH1A1 | |
| SCHEMBL24623215 | 0.80 | CYP2D6 (0.63) | CA12CA1CA9ALDH1A1HPGD | |
| SCHEMBL24623218 | 0.78 | ALDH1A1 (0.63) | POLBCA12CA1CA9ALDH1A1 | |
| SCHEMBL22632085 | 0.78 | ALDH1A1 (0.69) | POLBCA12CA1CA9ALDH1A1 | |
| SCHEMBL24623266 | 0.78 | RAD52 (0.48) | POLBCA12CA9ALDH1A1HPGD | |
| SCHEMBL24623257 | 0.77 | SLC18A1 (0.52) | CA12CA1CA9ALDH1A1HPGD | |
| SCHEMBL22632089 | 0.76 | ALDH1A1 (0.67) | POLBCA12CA1CA9ALDH1A1 | |
| SCHEMBL119578 | 0.76 | RAB9A (0.78) | POLBCA12CA1CA9ALDH1A1 | |
| SCHEMBL24623256 | 0.75 | IGLV6-57 (0.46) | POLBALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL6227542 | 0.71 | ALDH1A1 (0.74) | POLBCA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218722-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218722-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | AR, SHBG, NCOA1 | POLB 4344/4885CA12 1456/4885CA1 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.