Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | CCR8 | P51685 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884998 | 0.81 | TDO2 (0.42) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL6925972 | 0.80 | KDM4E (0.48) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL148991 | 0.79 | KMT2A (0.58) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL29625837 | 0.79 | KMT2A (0.58) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL27174137 | 0.79 | KMT2A (0.58) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL11885009 | 0.78 | MAPK14 (0.42) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| Triphenylene SCHEMBL29177920 | 0.78 | KMT2A (0.56) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL20005635 | 0.77 | KMT2A (0.50) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL22373940 | 0.77 | CCR1 (0.41) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 | |
| SCHEMBL24624526 | 0.74 | KDM4E (0.51) | MEN1KMT2AHSP90AA1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | NR0B2, FPR3, NPR3 | MEN1 1937/4885KMT2A 3303/4885HSP90AA1 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.