Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | TK2 | O00142 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589436 | 0.83 | DHFR (0.61) | DHFRTK2BCHETK1 | |
| SCHEMBL22801208 | 0.83 | DHFR (0.48) | DHFRSTING1TK2TK1 | |
| SCHEMBL22801261 | 0.83 | DHFR (0.48) | DHFRSTING1TK2TK1 | |
| SCHEMBL21178588 | 0.83 | DHFR (0.48) | DHFRSTING1TK2TK1 | |
| SCHEMBL21179129 | 0.83 | DHFR (0.48) | DHFRSTING1TK2TK1 | |
| SCHEMBL21178036 | 0.81 | DHFR (0.48) | DHFRSTING1TK2TK1 | |
| SCHEMBL22589427 | 0.80 | FGFR1 (0.51) | STING1FGFR1 | |
| SCHEMBL24625409 | 0.80 | FGFR1 (0.51) | STING1FGFR1 | |
| SCHEMBL21190322 | 0.74 | STING1 (0.37) | DHFRSTING1FGFR1 | |
| SCHEMBL21190271 | 0.74 | DHFR (0.51) | DHFRSTING1TK2BCHETK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220145-A1 | CYCLIC PHOSPHATE COMPOUNDS | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220145-A1 | CYCLIC PHOSPHATE COMPOUNDS | PYGL, ALPP, PHPT1 | DHFR 3080/4885STING1 1471/4885FGFR1 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.