Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | DGKA | P23743 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627714 | 0.97 | DNM1 (0.61) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627568 | 0.96 | MGLL (0.56) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627826 | 0.94 | MGLL (0.57) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627812 | 0.93 | MGLL (0.56) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627692 | 0.92 | DNM1 (0.66) | DNM1FAAHTHRBNAAADGKA | |
| SCHEMBL25076670 | 0.91 | DNM1 (0.59) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627811 | 0.90 | MGLL (0.59) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627505 | 0.90 | MGLL (0.55) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL24627544 | 0.90 | MGLL (0.55) | DNM1FAAHMGLLALDH1A1MAPT | |
| SCHEMBL17367558 | 0.89 | MGLL (0.57) | DNM1FAAHMGLLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218622-A1 | IONIZABLE LIPIDS AND METHODS OF MANUFACTURE AND USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218622-A1 | IONIZABLE LIPIDS AND METHODS OF MANUFACTURE AND USE THEREOF | NPC1L1, PLA2G4A, PLA2G2A | DNM1 1367/4885FAAH 1983/4885MGLL 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.