Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 5/20 | 0.33 |
| ▸ | MC3R | P41968 | 2/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462083 | 0.71 | ITGB1 (0.34) | ITGB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2460474 | 0.65 | OPRM1 (0.53) | POLBKMT2A | |
| SCHEMBL2460473 | 0.65 | OPRM1 (0.53) | POLBKMT2A | |
| SCHEMBL4982285 | 0.64 | CYP2C9 (0.55) | EPHX1POLBBCL2L1MCL1NPC1 | |
| SCHEMBL19862763 | 0.64 | NPC1 (0.38) | EPHX1POLBBCL2L1MCL1KMT2A | |
| SCHEMBL7659450 | 0.64 | CPN1 (0.51) | BCL2L1MCL1HRH1SLC6A2SLC6A4 | |
| SCHEMBL3516893 | 0.61 | POLB (0.48) | EPHX1POLBBCL2L1MCL1SLC6A2 | |
| SCHEMBL13391309 | 0.60 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18897353 | 0.60 | ALDH1A1 (0.39) | — | |
| SCHEMBL8328007 | 0.59 | HTR3A (0.41) | KCNH2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547696-A2 | FRAGMENTS OF THE PA SUBUNIT OF RNA DEPENDENT RNA POLYMERASE FROM PANDEMIC INFLUENZA VIRUS A 2009 H1N1, AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2013-01-23 | — | — | EP | claimed |
| WO-2011113579-A2 | INFLUENZA A 2009 PANDEMIC H1N1 POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2011-09-22 | — | — | WO | claimed |
| EP-2547696-A2 | FRAGMENTS OF THE PA SUBUNIT OF RNA DEPENDENT RNA POLYMERASE FROM PANDEMIC INFLUENZA VIRUS A 2009 H1N1, AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011113579-A2 | INFLUENZA A 2009 PANDEMIC H1N1 POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2011-09-22 | — | — | WO | disclosed |