Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460473 | 0.78 | OPRM1 (0.53) | POLBSSTR1SSTR4OPRM1OPRL1 | |
| SCHEMBL2460474 | 0.78 | OPRM1 (0.53) | POLBSSTR1SSTR4OPRM1OPRL1 | |
| SCHEMBL29658280 | 0.66 | DRD2 (0.56) | ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL29461356 | 0.65 | DRD2 (0.55) | POLBALDH1A1LMNASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL29461349 | 0.65 | DRD2 (0.55) | POLBALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL2463018 | 0.65 | KDM4E (0.51) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL2462081 | 0.65 | KDM4E (0.51) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL2462937 | 0.64 | EPHX1 (0.37) | NPC1RAB9APOLBEPHX1BCL2L1 | |
| SCHEMBL24249397 | 0.63 | HSD11B1 (0.46) | POLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19862764 | 0.63 | KMT2A (0.41) | NPC1RAB9APOLBEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044649-A1 | INFLUENZA A 2009 PANDEMIC H1N1 POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL (DE) | 2018-02-15 | — | — | US | disclosed |
| US-20180044649-A1 | INFLUENZA A 2009 PANDEMIC H1N1 POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL (DE) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044649-A1 | INFLUENZA A 2009 PANDEMIC H1N1 POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE | RNASE1, ACE, RNASEH1 | NPC1 2804/4885RAB9A 3153/4885POLB 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.