Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 10/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461321 | 0.88 | QPCT (0.51) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL31143361 | 0.77 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL6008269 | 0.77 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2459933 | 0.76 | MAPT (0.37) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL23122864 | 0.75 | QPCT (0.45) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2810219 | 0.73 | QPCT (0.41) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2461236 | 0.73 | QPCT (0.38) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2840581 | 0.72 | QPCT (0.40) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2457860 | 0.72 | PSMD11 (0.41) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2460352 | 0.71 | MAPT (0.38) | QPCTQPCTLMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | QPCT 3492/4885QPCTL 4285/4885MAPT 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.