Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315695 | 1.00 | GGT1 (0.37) | GGT1ALDH1A1ARG1ARG2TDP1 | |
| SCHEMBL25315606 | 1.00 | GGT1 (0.37) | GGT1ALDH1A1ARG1ARG2TDP1 | |
| SCHEMBL12581238 | 0.82 | ACLY (0.35) | ALDH1A1TDP1MEN1POLBCYP3A4 | |
| SCHEMBL21340475 | 0.80 | TSHR (0.38) | TDP1MEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL25315310 | 0.78 | ARG1 (0.47) | GGT1ARG1ARG2TDP1MEN1 | |
| SCHEMBL25314853 | 0.78 | ARG1 (0.47) | GGT1ARG1ARG2TDP1MEN1 | |
| SCHEMBL25314855 | 0.78 | ARG1 (0.47) | GGT1ARG1ARG2TDP1MEN1 | |
| Pivalate SCHEMBL9055894 | 0.77 | TDP1 (0.35) | ALDH1A1TDP1MAPTMEN1POLB | |
| SCHEMBL27807043 | 0.76 | L3MBTL1 (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL27807040 | 0.76 | L3MBTL1 (0.34) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214576-A1 | CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS | 中外製薬株式会社 | 2023-11-09 | — | — | WO | disclosed |
| US-20230235301-A1 | Compounds and Methods for Treating, Ameliorating, or Preventing Herpes Ocular Keratitis | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2023-07-27 | — | — | US | disclosed |
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230235301-A1 | Compounds and Methods for Treating, Ameliorating, or Preventing Herpes Ocular Keratitis | STING1, TK1, PCNA | GGT1 272/4885ALDH1A1 1454/4885ARG1 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.