SCHEMBL24636596

SCHEMBL24636596

C=COc1ccc([SiH3])cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473606 0.86 CHRNB2 (0.34) CHRNB2CHRNA4
SCHEMBL14289128 0.78 ALDH1A1 (0.44)
SCHEMBL11965976 0.78 ESR2 (0.33) CHRNB2CHRNA4
SCHEMBL13708120 0.77
SCHEMBL14605389 0.74 IDO1 (0.33) CHRNB2CHRNA4
SCHEMBL274124 0.74 CA1 (0.58)
SCHEMBL126186 0.74 ALDH1A1 (0.58) CHRNB2CHRNA4
SCHEMBL194091 0.74 ACHE (0.48)
SCHEMBL3391634 0.74 APP (0.39) CHRNB2CHRNA4
SCHEMBL194685 0.74 LMNA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022210901-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM 日産化学株式会社 2022-10-06 WO disclosed