Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24638023 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9385739 | 0.66 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3143287 | 0.65 | KDM4E (0.44) | KDM4EHSD17B10MAPTBRPF1KAT2B | |
| SCHEMBL17560670 | 0.64 | BRPF1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL21848235 | 0.62 | DAO (0.45) | KDM4EALDH1A1HPGDMAPTCA12 | |
| SCHEMBL24716706 | 0.62 | NQO2 (0.55) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29471261 | 0.62 | BRPF1 (0.50) | KDM4EHSD17B10MAPTATMBRPF1 | |
| SCHEMBL15519805 | 0.62 | BRPF1 (0.50) | KDM4EHSD17B10MAPTATMBRPF1 | |
| SCHEMBL23797332 | 0.62 | BRPF1 (0.49) | BRPF1KAT2BCA12BRD4CA9 | |
| SCHEMBL30099642 | 0.62 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192598-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-15 | — | — | WO | disclosed |