Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | NQO2 | P16083 | 4/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.38 |
| ▸ | BRD1 | O95696 | 3/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24638024 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17576626 | 0.71 | BRPF1 (0.52) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL30665881 | 0.71 | BRPF1 (0.52) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17576252 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17576471 | 0.67 | NQO2 (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29131019 | 0.67 | CYP19A1 (0.44) | KDM4EALDH1A1ADORA1CYP19A1NQO2 | |
| SCHEMBL30997245 | 0.66 | CGAS (0.32) | ALDH1A1GAAP2RX7S100BL3MBTL1 | |
| SCHEMBL3106868 | 0.65 | CYP19A1 (0.44) | ALDH1A1SMN1; SMN2ADORA1CYP19A1NQO2 | |
| SCHEMBL1003108 | 0.65 | NQO2 (0.63) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17576630 | 0.65 | S100B (0.58) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192598-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-15 | — | — | WO | disclosed |