SCHEMBL24639

SCHEMBL24639

Nc1ncnc2[nH]nnc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 8/20 0.42
PI4K2B Q8TCG2 8/20 0.42
PI4K2A Q9BTU6 8/20 0.42
PI4KB Q9UBF8 8/20 0.42
XDH P47989 2/20 0.42
LRRK2 Q5S007 2/20 0.42
RET P07949 2/20 0.42
ERAP1 Q9NZ08 1/20 0.38
ADORA2A P29274 8/20 0.35
ADORA1 P30542 7/20 0.35
LMNA P02545 1/20 0.33
DRD3 P35462 1/20 0.33
ADORA2B P29275 4/20 0.32
LIMK1 P53667 2/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
AHCY P23526 1/20 0.31
EGFR P00533 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CDC7 O00311 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15598533 0.77 YTHDC1 (0.33)
SCHEMBL7216711 0.77 ALDH1A1 (0.51) PI4KAPI4K2BPI4K2API4KBRET
SCHEMBL3445227 0.76 CHEK1 (0.37) ADORA2AADORA1ADORA3AURKADYRK1A
SCHEMBL7035657 0.76
SCHEMBL14322493 0.74 PDPK1 (0.36) XDHKDM4EADORA3CDK2
SCHEMBL14270443 0.71 FFAR2 (0.32)
SCHEMBL9129695 0.71 CYP1A2 (0.43)
SCHEMBL3695226 0.68 ADORA2A (0.34) ADORA2A
SCHEMBL29471407 0.67 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
SCHEMBL24640 0.67 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19903 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20250345406-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY SHATTUCK LABS INC (US) 2025-11-13 US claimed
US-20250325494-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-10-23 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-10-16 US claimed
EP-4630010-A1 ASYMMETRIC SHORT DUPLEX RNA WITH INTERSPERSED DEOXYRIBONUCLEOTIDES AS A GENE SILENCING TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
CN-1057652-A A kind of acyclic nucleotide of replacement and method of related intermediates thereof of preparing HOECHST AG (DE) 1992-01-08 CN claimed
EP-0463999-A1 Improvements in or relating to organic compounds SANDOZ LTD. (CH) 1992-01-02 EP claimed
EP-0418309-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER, Steven Albert (CH) 1991-03-27 EP claimed
WO-1989012060-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER STEVEN ALBERT (CH) 1989-12-14 WO claimed
EP-0098122-B1 PROCESSES FOR PRODUCING L-PROLINE BY FERMENTATION KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-05-31 EP claimed
EP-0069507-B1 HYDROCARBON COMPOSITIONS CONTAINING HETEROAROMATIC NITROGEN COMPOUNDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-09-10 EP claimed
EP-0098122-A2 Processes for producing L-proline by fermentation KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-01-11 EP claimed
EP-0069507-A2 Hydrocarbon compositions containing heteroaromatic nitrogen compounds EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-12 EP claimed
US-4367152-A Selected heteroaromatic nitrogen compounds as antioxidant/metal deactivators/electrical insulators in lubricating oils and petroleum liquid fuels EXXON RESEARCH AND ENGINEERING CO. (US) 1983-01-04 US claimed