Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639248 | 0.89 | NLRP3 (0.39) | OPRL1KCNH2NLRP3 | |
| SCHEMBL24639259 | 0.89 | NLRP3 (0.39) | OPRL1KCNH2NLRP3 | |
| SCHEMBL24640258 | 0.84 | KRAS (0.36) | — | |
| SCHEMBL24640260 | 0.84 | KRAS (0.36) | — | |
| SCHEMBL24640215 | 0.84 | NLRP3 (0.33) | OPRL1KCNH2NLRP3LTA4H | |
| SCHEMBL24640208 | 0.81 | AXL (0.35) | — | |
| SCHEMBL24640718 | 0.81 | AXL (0.35) | — | |
| SCHEMBL31244729 | 0.75 | HTR2C (0.42) | — | |
| SCHEMBL24640631 | 0.73 | SOS1 (0.35) | KCNH2 | |
| SCHEMBL24639280 | 0.72 | LTA4H (0.33) | OPRL1KCNH2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |