Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.46 |
| ▸ | NMT2 | O60551 | 4/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 8/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24642654 | 0.87 | SIRT6 (0.46) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL24642902 | 0.85 | NMT2 (0.33) | NMT1NMT2FURIN | |
| SCHEMBL24642903 | 0.82 | SIRT2 (0.34) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL26496635 | 0.80 | NMT1 (0.46) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL21437110 | 0.79 | NMT2 (0.45) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL8355213 | 0.79 | NMT2 (0.45) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL24642328 | 0.77 | CAPN1 (0.35) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL29392024 | 0.75 | FOLH1 (0.44) | NMT1NMT2FURINPRSS1 | |
| SCHEMBL21437116 | 0.75 | NMT2 (0.44) | NMT1NMT2SIRT6SIRT1FURIN | |
| SCHEMBL29714775 | 0.75 | NMT2 (0.44) | NMT1NMT2SIRT6SIRT1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170971-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州宜联生物医药有限公司 | 2022-08-18 | — | — | WO | disclosed |