SCHEMBL8355213

SCHEMBL8355213

CC(C)[C@H](NC(=O)CN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NMT2 O60551 1/20 0.45
▸ NMT1 P30419 1/20 0.45
▸ SIRT6 Q8N6T7 1/20 0.42
▸ SIRT1 Q96EB6 1/20 0.42
▸ FURIN P09958 8/20 0.42
▸ CTSL P07711 1/20 0.41
▸ PRSS1 P07477 2/20 0.40
▸ SLC15A2 Q16348 1/20 0.39
▸ FOLH1 Q04609 1/20 0.39
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ PCSK6 P29122 1/20 0.38
▸ GLO1 Q04760 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21437110 1.00 NMT2 (0.45) NMT2NMT1SIRT6SIRT1FURIN
SCHEMBL31454057 0.88 FURIN (0.42) NMT2NMT1SIRT6SIRT1FURIN
SCHEMBL27739976 0.88 PTGS1 (0.46) NMT2NMT1SIRT6SIRT1SLC15A2
SCHEMBL27739982 0.88 PTGS1 (0.46) NMT2NMT1SIRT6SIRT1SLC15A2
SCHEMBL4188063 0.88 PTGS1 (0.46) NMT2NMT1SIRT6SIRT1SLC15A2
SCHEMBL29389004 0.85 SLC15A2 (0.51) NMT2NMT1FURINCTSLSLC15A2
SCHEMBL29801954 0.84 PTGS1 (0.43) NMT2NMT1SIRT6SIRT1SLC15A2
SCHEMBL29714945 0.84 PTGS1 (0.43) NMT2NMT1SIRT6SIRT1SLC15A2
SCHEMBL30419451 0.84 PTGS1 (0.43) NMT2NMT1SIRT6SIRT1SLC15A2
SCHEMBL29355019 0.83 LMNA (0.47) ITGB3GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333541-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF EVOPOINT BIOSCIENCES CO LTD (CN) 2025-10-30 — — US claimed
EP-4484446-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2025-01-01 — — EP claimed
US-20240409628-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2024-12-12 — — US claimed
EP-4410372-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2024-08-07 — — EP claimed
WO-2023160651-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF 苏州信诺维医药科技股份有限公司 2023-08-31 — — WO claimed
WO-2023046202-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF 苏州信诺维医药科技股份有限公司 2023-03-30 — — WO claimed
WO-1999020300-A1 INHIBITION OF TUMOR CELL ADHESION TO TYPE IV COLLAGEN THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-04-29 — — WO claimed
EP-4653017-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF Tyligand Bioscience (Shanghai) Limited (CN) 2025-11-26 — — EP disclosed
US-20250333541-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF EVOPOINT BIOSCIENCES CO LTD (CN) 2025-10-30 — — US disclosed
US-20250135018-A1 CAMPTOTHECIN PEPTIDE CONJUGATES SEAGEN INC (US) 2025-05-01 — — US disclosed
EP-4484446-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2025-01-01 — — EP disclosed
US-20240409628-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2024-12-12 — — US disclosed
CN-118873678-A Antibody-conjugated drugs and uses thereof 泰励生物科技(上海)有限公司 2024-11-01 — — CN disclosed
EP-4410372-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2024-08-07 — — EP disclosed
WO-2024153127-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF 泰励生物科技(上海)有限公司 2024-07-25 — — WO disclosed
WO-2023160651-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF 苏州信诺维医药科技股份有限公司 2023-08-31 — — WO disclosed
WO-2023046202-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF 苏州信诺维医药科技股份有限公司 2023-03-30 — — WO disclosed
US-20220193069-A1 CAMPTOTHECIN PEPTIDE CONJUGATES SEAGEN INC (US) 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333541-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF TNFRSF9, F13B, FCGR1A NMT2 760/4885NMT1 807/4885SIRT6 1555/4885
US-20240409628-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF EPCAM, CNTN1, STX18 NMT2 949/4885NMT1 1445/4885SIRT6 3754/4885
US-20250135018-A1 CAMPTOTHECIN PEPTIDE CONJUGATES VIP, DCLRE1A, UACA NMT2 104/4885NMT1 94/4885SIRT6 2650/4885
US-20220193069-A1 CAMPTOTHECIN PEPTIDE CONJUGATES VIP, DCLRE1A, UACA NMT2 104/4885NMT1 94/4885SIRT6 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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