Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203770 | 1.00 | LMNA (0.34) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL3880292 | 0.80 | LMNA (0.36) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL13259999 | 0.80 | ALDH1A1 (0.36) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL200337 | 0.80 | KDM4E (0.32) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL4415495 | 0.78 | KDM4E (0.31) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL12256195 | 0.77 | KDM4E (0.31) | LMNAKDM4E | |
| SCHEMBL13532353 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1USP2 | |
| SCHEMBL75227 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL7048034 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL18714194 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164503-A1 | REPROCESSABLE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-08-04 | — | — | WO | disclosed |