Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24643274 | 1.00 | LMNA (0.34) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL3880292 | 0.80 | LMNA (0.36) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL13259999 | 0.80 | ALDH1A1 (0.36) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL200337 | 0.80 | KDM4E (0.32) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL4415495 | 0.78 | KDM4E (0.31) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL12256195 | 0.77 | KDM4E (0.31) | LMNAKDM4E | |
| SCHEMBL13532353 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1USP2 | |
| SCHEMBL75227 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL7048034 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1GAA | |
| SCHEMBL18714194 | 0.77 | ALDH1A1 (0.35) | LMNAKDM4EALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372844-B1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INST OF TECHN (US) | 2011-01-05 | — | — | EP | claimed |
| US-7101496-B2 | Thermoplastic norbornene resin based optical film | JSR CORPORATION (JP) | 2006-09-05 | — | — | US | claimed |
| US-6838489-B2 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | CYMETECH, LLC (US) | 2005-01-04 | — | — | US | claimed |
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | STERLING JA, L.C. | 2003-07-31 | — | — | US | claimed |
| CN-117586452-A | Cycloolefin composition and optical resin material | 杭州睿丰融创科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| US-10915019-B2 | Photosensitive compositions, color filter and microlens derived therefrom | PROMERUS, LLC (US) | 2021-02-09 | — | — | US | disclosed |
| EP-3197881-B1 | DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM | PROMERUS LLC (US) | 2020-04-29 | — | — | EP | disclosed |
| US-10634998-B2 | Photoimageable polyolefin compositions containing photobase generators | PROMERUS, LLC (US) | 2020-04-28 | — | — | US | disclosed |
| US-10409160-B2 | Photoimageable polyolefin compositions containing photobase generators | PROMERUS, LLC (US) | 2019-09-10 | — | — | US | disclosed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-10174171-B2 | Nanoporous films derived from polycyclo-olefinic block polymers | PROMERUS, LLC (US) | 2019-01-08 | — | — | US | disclosed |
| WO-1996032421-A1 | OLEFIN METATHESIS REACTIONS IN CARBON DIOXIDE MEDIUM | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-10-17 | — | — | WO | disclosed |
| WO-1996007674-A1 | PROCESS FOR THE PACKAGED POLYMERIZATION OF OLEFINIC MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| US-5491206-A | MOLDING MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0694575-A1 | Process for the in-line polymerization of olefinic monomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
| WO-1996001851-A1 | SUPERATMOSPHERIC REACTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-25 | — | — | WO | disclosed |
| WO-1996001850-A1 | SUPERATMOSPHERIC REACTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-25 | — | — | WO | disclosed |
| US-5296566-A | Composition containing ring-strained non-conjugated cyclic olefin, cationic organometallic ruthenium or osmium catalyst having polyene ligand | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-5198511-A | Polymerizable compositions containing olefin metathesis catalysts and cocatalysts, and methods of use therefor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | NQO1, NIT2, ALOX5 | LMNA 2093/4885KDM4E 4592/4885ALDH1A1 1236/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | LMNA 1545/4885KDM4E 1745/4885ALDH1A1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.