Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR4 | P46093 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692001 | 0.85 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL20129619 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14863940 | 0.83 | HTR2C (0.43) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL25271016 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2POLBALDH1A1L3MBTL1CXCR4 | |
| SCHEMBL2899901 | 0.83 | ALDH1A1 (0.63) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL92331 | 0.83 | L3MBTL1 (0.56) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL23419850 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL20133743 | 0.83 | GAA (0.57) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL4767938 | 0.82 | ALDH1A1 (0.61) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| Bromide SCHEMBL28426487 | 0.81 | L3MBTL1 (0.54) | MEN1KMT2APOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | TGFBR2, SMAD2, ACVR2A | MGLL 4783/4885SMN1; SMN2 3976/4885MEN1 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.