Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692001 | 0.85 | MEN1 (0.47) | ALDH1A1POLBL3MBTL1CXCR4SMN1; SMN2 | |
| SCHEMBL24648953 | 0.83 | MGLL (0.43) | ALDH1A1POLBL3MBTL1CXCR4SMN1; SMN2 | |
| SCHEMBL2899901 | 0.83 | ALDH1A1 (0.63) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL25271016 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBL3MBTL1CXCR4SMN1; SMN2 | |
| SCHEMBL14863940 | 0.83 | HTR2C (0.43) | ALDH1A1POLBL3MBTL1CXCR4SMN1; SMN2 | |
| SCHEMBL92331 | 0.83 | L3MBTL1 (0.56) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4767938 | 0.82 | ALDH1A1 (0.61) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| Bromide SCHEMBL28426487 | 0.81 | L3MBTL1 (0.54) | ALDH1A1POLBL3MBTL1CXCR4MEN1 | |
| Hydrochloric Acid SCHEMBL4768580 | 0.81 | L3MBTL1 (0.54) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL7996202 | 0.81 | ENPP2 (0.51) | POLBL3MBTL1CXCR4HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | ALDH1A1 3942/4885POLB 2449/4885L3MBTL1 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.