Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9368920 | 0.87 | DRD3 (0.48) | PKMALDH1A1GAATBXAS1DRD2 | |
| SCHEMBL24650300 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAANLRP3CYP4F2CYP4A11 | |
| SCHEMBL24650294 | 0.86 | DRD2 (0.41) | DRD2DRD3SMN1; SMN2 | |
| SCHEMBL24650352 | 0.85 | CYP4F2 (0.49) | ALDH1A1GAACYP4F2CYP4A11TBXAS1 | |
| SCHEMBL24650447 | 0.79 | USP2 (0.45) | ALDH1A1GAADRD2DRD3SMN1; SMN2 | |
| SCHEMBL24650493 | 0.78 | ADRA1A (0.41) | PKMALDH1A1TBXAS1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24650477 | 0.78 | DPP4 (0.36) | PKMALDH1A1GAASMN1; SMN2 | |
| SCHEMBL24650479 | 0.78 | SMN1; SMN2 (0.39) | PKMALDH1A1GAAL3MBTL1DRD2 | |
| SCHEMBL24650299 | 0.78 | TSHR (0.51) | ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL26650335 | 0.78 | DRD2 (0.41) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |