Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26715449 | 0.84 | TSHR (0.53) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL24650297 | 0.84 | TRPA1 (0.46) | TSHRALDH1A1HSD17B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL6647894 | 0.82 | TRPA1 (0.45) | TSHRALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL24650296 | 0.78 | PKM (0.40) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL24650790 | 0.77 | CA12 (0.53) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL24650874 | 0.77 | HPGD (0.42) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL24650890 | 0.77 | CA1 (0.39) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL24650295 | 0.77 | DRD2 (0.45) | ALDH1A1HSP90AA1ALOX15 | |
| SCHEMBL24650875 | 0.76 | ADRA1A (0.58) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL24650300 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |