Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650349 | 0.91 | GAA (0.42) | GAAKDM4EHSD17B10NPSR1POLB | |
| SCHEMBL24650543 | 0.91 | CHRNB2 (0.40) | CHRNB2CHRNA4PPARDPOLBHPGD | |
| SCHEMBL24650316 | 0.89 | BRD4 (0.42) | GAAKDM4EHSD17B10CHRNB2CHRNA4 | |
| SCHEMBL24650332 | 0.86 | HSD17B1 (0.40) | CA1CA2CA7CA9CA14 | |
| SCHEMBL24650433 | 0.83 | PPARD (0.41) | KDM4EHSD17B10CHRNB2CHRNA4PPARD | |
| SCHEMBL24650478 | 0.82 | POLB (0.39) | GAAKDM4EHSD17B10POLBALDH1A1 | |
| SCHEMBL24650334 | 0.81 | OPRM1 (0.39) | GAAKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL24650515 | 0.81 | NQO2 (0.41) | GAAKDM4EPPARDPOLBALDH1A1 | |
| SCHEMBL24650424 | 0.81 | PPARD (0.47) | CHRNB2CHRNA4PPARDPPARGPPARA | |
| SCHEMBL24651117 | 0.81 | PPARD (0.43) | GAAKDM4EHSD17B10NPSR1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |