Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23017953 | 0.72 | THRB (0.79) | THRBTHRA | |
| SCHEMBL4072199 | 0.72 | MCL1 (0.62) | MCL1L3MBTL1 | |
| SCHEMBL15464819 | 0.70 | MCL1 (0.70) | MCL1L3MBTL1 | |
| SCHEMBL16503434 | 0.69 | MCL1 (0.68) | MCL1L3MBTL1THRBTHRA | |
| SCHEMBL3731595 | 0.68 | L3MBTL1 (0.67) | MCL1L3MBTL1 | |
| SCHEMBL3723832 | 0.67 | L3MBTL1 (0.66) | MCL1L3MBTL1 | |
| SCHEMBL12207085 | 0.66 | MCL1 (0.62) | MCL1L3MBTL1THRBTHRA | |
| SCHEMBL45405 | 0.65 | USP2 (0.49) | L3MBTL1THRBTHRA | |
| SCHEMBL4880533 | 0.65 | USP2 (0.49) | L3MBTL1THRBTHRA | |
| SCHEMBL16480582 | 0.65 | MCL1 (0.69) | MCL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |