Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650388 | 0.93 | MEN1 (0.44) | MEN1KMT2AGAANPSR1ALDH1A1 | |
| SCHEMBL24650304 | 0.92 | ALDH1A1 (0.42) | MEN1KMT2AGAANPSR1ALDH1A1 | |
| SCHEMBL24650307 | 0.90 | MEN1 (0.44) | MEN1KMT2AGAANPSR1ALDH1A1 | |
| SCHEMBL24650391 | 0.89 | CA1 (0.42) | MEN1KMT2AGAAALDH1A1CA1 | |
| SCHEMBL24650411 | 0.87 | PDE4A (0.45) | KMT2AALDH1A1CA1CA2ACHE | |
| SCHEMBL24650386 | 0.85 | HPGD (0.46) | MEN1KMT2AGAANPSR1ALDH1A1 | |
| SCHEMBL24650378 | 0.85 | CA1 (0.42) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL24650918 | 0.83 | LMNA (0.40) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL24650249 | 0.82 | PDE4A (0.39) | KMT2AALDH1A1POLBCA1CA2 | |
| SCHEMBL24650312 | 0.81 | CASP3 (0.40) | MEN1KMT2AGAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |