Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650766 | 0.89 | GLA (0.45) | CYP1A2MAPTCYP2C9ALDH1A1 | |
| SCHEMBL24650905 | 0.88 | HTR1A (0.43) | AADATHTR1ADRD2DRD3HTR2A | |
| SCHEMBL24651120 | 0.86 | HTR1A (0.42) | AADATHTR1ADRD2DRD3HTR2A | |
| SCHEMBL24651122 | 0.84 | HTR1A (0.40) | AADATHTR1ADRD2DRD3HTR2A | |
| SCHEMBL24650901 | 0.84 | HTR1A (0.40) | AADATHTR1ADRD2DRD3HTR2A | |
| SCHEMBL9035471 | 0.83 | SMN1; SMN2 (0.42) | HTR1AMTNR1AMTNR1BCA12CA1 | |
| SCHEMBL24650867 | 0.83 | PTGFR (0.40) | AADATHTR1ADRD2DRD3HTR2A | |
| SCHEMBL9035210 | 0.82 | MTNR1A (0.41) | HTR1AHTR2AMTNR1AMTNR1BCA12 | |
| SCHEMBL24651137 | 0.80 | HTR1A (0.44) | AADATHTR1AHTR2AMTNR1AMTNR1B | |
| SCHEMBL24650839 | 0.80 | AADAT (0.44) | AADATHTR1ADRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |