Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650867 | 0.96 | PTGFR (0.40) | HTR1AMTNR1AMTNR1BHTR2ALMNA | |
| SCHEMBL24651120 | 0.92 | HTR1A (0.42) | HTR1AMTNR1AMTNR1BHTR2ALMNA | |
| SCHEMBL24651100 | 0.89 | L3MBTL1 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL24651130 | 0.89 | HTR1A (0.42) | HTR1AMTNR1AMTNR1BHTR2AAADAT | |
| SCHEMBL24650872 | 0.86 | HTR1A (0.40) | HTR1AMTNR1AMTNR1BHTR2AAADAT | |
| SCHEMBL24650780 | 0.84 | AADAT (0.42) | HTR1AMTNR1AMTNR1BHTR2AAADAT | |
| SCHEMBL24651137 | 0.84 | HTR1A (0.44) | HTR1AMTNR1AMTNR1BHTR2AAADAT | |
| SCHEMBL24650495 | 0.82 | TDP1 (0.40) | HTR1AMTNR1AMTNR1BHTR2AALOX15 | |
| SCHEMBL24651107 | 0.82 | HTR1A (0.37) | HTR1AMAPTDRD2DRD3 | |
| SCHEMBL24651123 | 0.81 | MTNR1A (0.39) | MTNR1AMTNR1BHTR2ALMNAAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |