Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650775 | 0.90 | ALOX15 (0.45) | TSHRKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL24650792 | 0.90 | NQO2 (0.41) | CHRNB2CHRNA4PPARDTSHRKMT2A | |
| SCHEMBL24650831 | 0.90 | CHRNB2 (0.43) | CHRNB2CHRNA4PPARDKMT2ACA1 | |
| SCHEMBL24650827 | 0.87 | PPARD (0.46) | CHRNB2CHRNA4PPARDTSHRKMT2A | |
| SCHEMBL24650772 | 0.84 | KDM4E (0.40) | TSHRKMT2ACA1CA2CA7 | |
| SCHEMBL24650273 | 0.81 | BRD4 (0.41) | CHRNB2CHRNA4PPARDKMT2APKM | |
| SCHEMBL24651117 | 0.80 | PPARD (0.43) | CHRNB2CHRNA4PPARDCA1CA2 | |
| SCHEMBL24650855 | 0.80 | MAPT (0.41) | TSHRKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL24650845 | 0.80 | NQO2 (0.44) | CHRNB2CHRNA4PPARDKMT2AALDH1A1 | |
| SCHEMBL24650763 | 0.80 | ALDH1A1 (0.43) | TSHRKMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |