Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406870 | 0.84 | CYP2C19 (0.48) | MAPTATMHTTCYP1A2TSHR | |
| SCHEMBL8407013 | 0.84 | CYP2C19 (0.48) | MAPTATMHTTCYP1A2TSHR | |
| SCHEMBL24650850 | 0.83 | CYP3A4 (0.38) | MAPK1HTTCYP1A2TSHRHSD17B10 | |
| SCHEMBL24650760 | 0.82 | OPRM1 (0.40) | MAPTTSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL24650772 | 0.82 | KDM4E (0.40) | MAPTMAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL24650758 | 0.80 | CA12 (0.44) | MAPTATMMAPK1HTTCYP1A2 | |
| SCHEMBL24650792 | 0.80 | NQO2 (0.41) | MAPTTSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL24650797 | 0.80 | CHRNB2 (0.43) | MAPTTSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL24650775 | 0.80 | ALOX15 (0.45) | MAPTMAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL24650763 | 0.80 | ALDH1A1 (0.43) | MAPTTSHRHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |