Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650760 | 0.89 | OPRM1 (0.40) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24650836 | 0.85 | OPRM1 (0.40) | ALDH1A1MEN1KMT2ADPP4SHBG | |
| SCHEMBL24650775 | 0.84 | ALOX15 (0.45) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24650797 | 0.84 | CHRNB2 (0.43) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24650855 | 0.82 | MAPT (0.41) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24650267 | 0.80 | SHBG (0.44) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24651104 | 0.79 | HSD17B1 (0.44) | KMT2AGAADPP4SHBGCA12 | |
| SCHEMBL24650758 | 0.77 | CA12 (0.44) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8037590 | 0.77 | MEN1 (0.40) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8410014 | 0.77 | MEN1 (0.40) | KDM4EALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |