Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 5/20 | 0.40 |
| ▸ | HIPK1 | Q86Z02 | 5/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 5/20 | 0.40 |
| ▸ | HIPK3 | Q9H422 | 5/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | GRK1 | Q15835 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461206 | 0.87 | DYRK1A (0.54) | DYRK1AACVR1PIM1PIM3PIM2 | |
| SCHEMBL28048555 | 0.82 | DYRK1A (0.72) | DYRK1ACLK2CLK4CLK1PIK3CD | |
| SCHEMBL2457425 | 0.75 | DYRK1A (0.55) | DYRK1ACLK2CLK4CLK1PIK3CD | |
| SCHEMBL2455181 | 0.74 | PIM1 (0.43) | DYRK1AACVR1PIM1PIM3PIM2 | |
| SCHEMBL592989 | 0.74 | DYRK1A (0.62) | DYRK1AALKPIK3CDMEN1ALDH1A1 | |
| SCHEMBL29375136 | 0.74 | DYRK1A (0.62) | DYRK1AALKPIK3CDMEN1ALDH1A1 | |
| SCHEMBL8076216 | 0.73 | DYRK1A (0.60) | DYRK1ACLK2CLK4CLK1PIK3CD | |
| SCHEMBL8080835 | 0.73 | DYRK1A (0.60) | DYRK1ACLK2CLK4CLK1PIK3CD | |
| SCHEMBL10337032 | 0.73 | DYRK1A (0.60) | DYRK1ACLK2CLK4CLK1PIK3CD | |
| SCHEMBL27606654 | 0.73 | DYRK1A (0.60) | DYRK1APIK3CDMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | DYRK1A 4134/4885ACVR1 277/4885PIM1 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.