SCHEMBL2465480

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2581742	0.93	HRH3 (0.43)	HRH3BCHEACHEKCNH2POLB
	SCHEMBL2461274	0.88	TUBB4A (0.36)	HRH3
	SCHEMBL2584834	0.87	HTR1A (0.38)	ALDH1A1KDM4EGAAHPGDHRH3
	SCHEMBL2585559	0.85	HTR1A (0.36)	GSK3BQPCT
	SCHEMBL12160475	0.83	BCHE (0.39)	BCL9CTNNB1ALDH1A1KDM4EHPGD
	SCHEMBL2489928	0.83	HTR1A (0.41)	BCL9CTNNB1ALDH1A1KDM4EGAA
	SCHEMBL7913573	0.83	HRH3 (0.37)	BCL9CTNNB1HRH3HTR2A
	SCHEMBL7909989	0.83	ESR1 (0.39)	HRH3BCHEACHE
	Hydrochloric Acid SCHEMBL2578962	0.82	ESR1 (0.38)	HRH3BCHEACHE
	Hydrochloric Acid SCHEMBL2584977	0.82	HRH3 (0.36)	BCL9CTNNB1HRH3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.