SCHEMBL2584834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2585559	0.98	HTR1A (0.36)	HTR1AKDRFLT1FLT4PARP1
	SCHEMBL2463783	0.88	FLT1 (0.32)	KDRFLT1FLT4
	SCHEMBL2465480	0.87	BCL9 (0.40)	HTR2AALDH1A1CYP1A2CHRM2CHRM1
	SCHEMBL2581742	0.80	HRH3 (0.43)	KCNH2HRH3POLBMAPT
	SCHEMBL2461274	0.74	TUBB4A (0.36)	HRH3
	SCHEMBL2575816	0.72	KDM4E (0.36)	PARP1ALDH1A1TSHRMAPK1KDM4E
	SCHEMBL12160475	0.70	BCHE (0.39)	HTR2AALDH1A1TSHRCYP1A2CHRM2
	SCHEMBL7913573	0.70	HRH3 (0.37)	HTR1AHTR2AHRH3
	SCHEMBL7909989	0.70	ESR1 (0.39)	HTR1AHRH3
	SCHEMBL7904087	0.70	DRD2 (0.36)	ALDH1A1TSHRMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.