Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169042 | 0.87 | PRMT5 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL21849188 | 0.85 | CHRNB2 (0.41) | CYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL25744953 | 0.78 | AKT1 (0.35) | — | |
| SCHEMBL24768968 | 0.76 | HDAC6 (0.33) | — | |
| SCHEMBL91426 | 0.75 | CYP1A1 (0.42) | CYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL25635024 | 0.74 | CYP11B1 (0.33) | CYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL24702065 | 0.74 | CCR6 (0.41) | — | |
| SCHEMBL19055348 | 0.73 | CYP3A4 (0.48) | CYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL19240345 | 0.73 | ACHE (0.49) | — | |
| SCHEMBL25744912 | 0.73 | SCN9A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | CYP11B1 1168/4885CYP11B2 1579/4885CHRNB2 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.